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cruises to south america

MSC Cruises to South America

MSC Cruises South America cruise vacations provide guests with a chance to experience a South American cruise in Italian style and elegance. MSC Cruises to South America introduce travelers to the sights and sounds of the region, from the serenity of private beaches to the bustling city life of Rio de Janeiro, and provide excellent ships that rival the finest hotels in Italy. Onboard MSC Cruise Line, passengers can relax in on-deck swimming pools, enjoy fine Italian 7-course meals, or enjoy an evening show for the family. With all MSC Cruises to South America, kids sail free, making this a valuable family choice.

Showing 126-150 of 160 results
Roundtrip
7-Night South America Cruise
$950
MSC Cruises – MSC Splendida
9 Reviews
Departs Mar 06, 2025 from Itajaí, Brazil
Up to 1 deal including an Avoya Exclusive
Roundtrip
7-Night South America Cruise
$1,280
MSC Cruises – MSC Splendida
9 Reviews
Departs Mar 07, 2025 from Santos, Brazil
Up to 1 deal including an Avoya Exclusive
Roundtrip
7-Night South America Cruise
$736
43% Off List
MSC Cruises – MSC Grandiosa
2 Reviews
Departs Mar 08, 2025 from Santos, Brazil
Up to 3 deals including an Avoya Exclusive
Roundtrip
7-Night South America Cruise
$738
45% Off List
MSC Cruises – MSC Seaview
5 Reviews
Departs Mar 09, 2025 from Santos, Brazil
Up to 2 deals including an Avoya Exclusive
Roundtrip
9-Night South America Cruise
$1,381
30% Off List
MSC Cruises – MSC Poesia
29 Reviews
Departs Mar 09, 2025 from Buenos Aires, Argentina
Up to 3 deals including an Avoya Exclusive
Roundtrip
7-Night South America Cruise
$1,262
MSC Cruises – MSC Splendida
9 Reviews
Departs Mar 10, 2025 from Buenos Aires, Argentina
Up to 1 deal including an Avoya Exclusive
Roundtrip
9-Night South America Cruise
$1,324
39% Off List
MSC Cruises – MSC Poesia
29 Reviews
Departs Mar 10, 2025 from Montevideo, Uruguay
Up to 3 deals including an Avoya Exclusive
Roundtrip
7-Night South America Cruise
$708
44% Off List
MSC Cruises – MSC Grandiosa
2 Reviews
Departs Mar 11, 2025 from Salvador, Brazil
Up to 3 deals including an Avoya Exclusive
Roundtrip
7-Night South America Cruise
$753
45% Off List
MSC Cruises – MSC Grandiosa
2 Reviews
Departs Mar 12, 2025 from Maceió, Brazil
Up to 3 deals including an Avoya Exclusive
Roundtrip
7-Night South America Cruise
$950
MSC Cruises – MSC Splendida
9 Reviews
Departs Mar 13, 2025 from Itajaí, Brazil
Up to 1 deal including an Avoya Exclusive
Roundtrip
7-Night South America Cruise
$1,256
MSC Cruises – MSC Splendida
9 Reviews
Departs Mar 14, 2025 from Santos, Brazil
Up to 1 deal including an Avoya Exclusive
Roundtrip
7-Night South America Cruise
$736
43% Off List
MSC Cruises – MSC Grandiosa
2 Reviews
Departs Mar 15, 2025 from Santos, Brazil
Up to 3 deals including an Avoya Exclusive
Roundtrip
4-Night South America Cruise
$508
46% Off List
MSC Cruises – MSC Seaview
5 Reviews
Departs Mar 16, 2025 from Santos, Brazil
Up to 2 deals including an Avoya Exclusive
Roundtrip
7-Night South America Cruise
$1,212
MSC Cruises – MSC Splendida
9 Reviews
Departs Mar 17, 2025 from Buenos Aires, Argentina
Up to 1 deal including an Avoya Exclusive
Roundtrip
7-Night South America Cruise
$708
44% Off List
MSC Cruises – MSC Grandiosa
2 Reviews
Departs Mar 18, 2025 from Salvador, Brazil
Up to 3 deals including an Avoya Exclusive
Roundtrip
8-Night South America Cruise
$1,261
30% Off List
MSC Cruises – MSC Poesia
29 Reviews
Departs Mar 18, 2025 from Buenos Aires, Argentina
Up to 3 deals including an Avoya Exclusive
Roundtrip
7-Night South America Cruise
$783
45% Off List
MSC Cruises – MSC Grandiosa
2 Reviews
Departs Mar 19, 2025 from Maceió, Brazil
Up to 3 deals including an Avoya Exclusive
Roundtrip
8-Night South America Cruise
$1,073
38% Off List
MSC Cruises – MSC Poesia
29 Reviews
Departs Mar 19, 2025 from Montevideo, Uruguay
Up to 3 deals including an Avoya Exclusive
Roundtrip
4-Night South America Cruise
$511
46% Off List
MSC Cruises – MSC Seaview
5 Reviews
Departs Mar 20, 2025 from Santos, Brazil
Up to 2 deals including an Avoya Exclusive
Roundtrip
7-Night South America Cruise
$1,049
MSC Cruises – MSC Splendida
9 Reviews
Departs Mar 20, 2025 from Itajaí, Brazil
Up to 1 deal including an Avoya Exclusive
Roundtrip
7-Night South America Cruise
$1,370
MSC Cruises – MSC Splendida
9 Reviews
Departs Mar 21, 2025 from Santos, Brazil
Up to 1 deal including an Avoya Exclusive
Roundtrip
7-Night South America Cruise
$736
43% Off List
MSC Cruises – MSC Grandiosa
2 Reviews
Departs Mar 22, 2025 from Santos, Brazil
Up to 3 deals including an Avoya Exclusive
Roundtrip
3-Night South America Cruise
$460
45% Off List
MSC Cruises – MSC Seaview
5 Reviews
Departs Mar 24, 2025 from Santos, Brazil
Up to 2 deals including an Avoya Exclusive
Roundtrip
7-Night South America Cruise
$708
44% Off List
MSC Cruises – MSC Grandiosa
2 Reviews
Departs Mar 25, 2025 from Salvador, Brazil
Up to 3 deals including an Avoya Exclusive
Roundtrip
7-Night South America Cruise
$853
45% Off List
MSC Cruises – MSC Grandiosa
2 Reviews
Departs Mar 26, 2025 from Maceió, Brazil
Up to 3 deals including an Avoya Exclusive
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