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cruises to panama canal

MSC Cruises to Panama Canal

MSC Cruises Panama Canal sailings give guests the privilege of enjoying two oceans, two coasts, and many exciting destinations along the way. Sailing from Florida to the Caribbean, passing through the Panama Canal, and traveling the coast of Central America and Mexico, guests onboard MSC Cruise Line will encounter several cultures and watch the landscape transform on their Panama cruise. MSC Cruises to the Panama Canal invite guests to relax into elegant cabins, enjoy hours of onboard entertainment, and experience the destination in a distinctly Italian style.

Showing 1-5 of 5 results
35-Night Panama Canal Cruise
$2,649
51% Off List
MSC Cruises – MSC Poesia
29 Reviews
Departs Apr 06, 2026 from Rome (Civitavecchia), Italy
Up to 2 deals
34-Night Panama Canal Cruise
$2,949
53% Off List
MSC Cruises – MSC Poesia
29 Reviews
Departs Apr 07, 2026 from Genoa, Italy
Up to 1 deal
33-Night Panama Canal Cruise
$2,519
51% Off List
MSC Cruises – MSC Poesia
29 Reviews
Departs Apr 08, 2026 from Marseille, France
Up to 2 deals
32-Night Panama Canal Cruise
$2,449
51% Off List
MSC Cruises – MSC Poesia
29 Reviews
Departs Apr 09, 2026 from Barcelona, Spain
Up to 2 deals
18-Night Panama Canal Cruise
$1,608
51% Off List
MSC Cruises – MSC Poesia
29 Reviews
Departs Apr 23, 2026 from Miami, Florida
Up to 2 deals
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