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MSC Cruises to Africa

MSC Cruises Africa cruises are diverse and exciting, exploring everything from ancient pyramids in Egypt to guided safaris in natural reserves. Onboard the MSC Sinfonia, which sails all of MSC Cruise line’s African Cruises, guests will enjoy distinct Italian style, comfortable accommodations, countless activities, and more. In addition, on all MSC Cruises to Africa, kids sail free!

Showing 126-150 of 166 results
Roundtrip
3-Night Africa Cruise
$309
MSC Cruises – MSC Opera
5 Reviews
Departs Feb 06, 2026 from Durban, South Africa
Up to 1 deal including an Avoya Exclusive
Roundtrip
7-Night Africa Cruise
$713
MSC Cruises – MSC Musica
4 Reviews
Departs Feb 06, 2026 from Las Palmas, Spain
Up to 2 deals including an Avoya Exclusive
Roundtrip
7-Night Africa Cruise
$718
MSC Cruises – MSC Musica
4 Reviews
Departs Feb 07, 2026 from Funchal, Madeira Islands, Portugal
Up to 2 deals including an Avoya Exclusive
Roundtrip
7-Night Africa Cruise
$714
MSC Cruises – MSC Musica
4 Reviews
Departs Feb 08, 2026 from Santa Cruz de Tenerife, Spain
Up to 2 deals including an Avoya Exclusive
Roundtrip
4-Night Africa Cruise
$379
MSC Cruises – MSC Opera
5 Reviews
Departs Feb 09, 2026 from Durban, South Africa
Up to 1 deal including an Avoya Exclusive
Roundtrip
3-Night Africa Cruise
$309
MSC Cruises – MSC Opera
5 Reviews
Departs Feb 13, 2026 from Durban, South Africa
Up to 1 deal including an Avoya Exclusive
Roundtrip
7-Night Africa Cruise
$713
MSC Cruises – MSC Musica
4 Reviews
Departs Feb 13, 2026 from Las Palmas, Spain
Up to 2 deals including an Avoya Exclusive
Roundtrip
7-Night Africa Cruise
$718
MSC Cruises – MSC Musica
4 Reviews
Departs Feb 14, 2026 from Funchal, Madeira Islands, Portugal
Up to 2 deals including an Avoya Exclusive
Roundtrip
7-Night Africa Cruise
$714
MSC Cruises – MSC Musica
4 Reviews
Departs Feb 15, 2026 from Santa Cruz de Tenerife, Spain
Up to 2 deals including an Avoya Exclusive
Roundtrip
4-Night Africa Cruise
$379
MSC Cruises – MSC Opera
5 Reviews
Departs Feb 16, 2026 from Durban, South Africa
Up to 1 deal including an Avoya Exclusive
Roundtrip
7-Night Africa Cruise
$1,021
MSC Cruises – MSC Musica
4 Reviews
Departs Feb 20, 2026 from Las Palmas, Spain
Up to 2 deals including an Avoya Exclusive
Roundtrip
7-Night Africa Cruise
$718
MSC Cruises – MSC Musica
4 Reviews
Departs Feb 21, 2026 from Funchal, Madeira Islands, Portugal
Up to 2 deals including an Avoya Exclusive
Roundtrip
7-Night Africa Cruise
$714
MSC Cruises – MSC Musica
4 Reviews
Departs Feb 22, 2026 from Santa Cruz de Tenerife, Spain
Up to 2 deals including an Avoya Exclusive
Roundtrip
4-Night Africa Cruise
$389
MSC Cruises – MSC Opera
5 Reviews
Departs Feb 23, 2026 from Durban, South Africa
Up to 1 deal including an Avoya Exclusive
Roundtrip
7-Night Africa Cruise
$997
MSC Cruises – MSC Musica
4 Reviews
Departs Feb 27, 2026 from Las Palmas, Spain
Up to 2 deals including an Avoya Exclusive
Roundtrip
7-Night Africa Cruise
$698
MSC Cruises – MSC Musica
4 Reviews
Departs Feb 28, 2026 from Funchal, Madeira Islands, Portugal
Up to 2 deals including an Avoya Exclusive
Roundtrip
7-Night Africa Cruise
$694
MSC Cruises – MSC Musica
4 Reviews
Departs Mar 01, 2026 from Santa Cruz de Tenerife, Spain
Up to 2 deals including an Avoya Exclusive
Roundtrip
4-Night Africa Cruise
$389
MSC Cruises – MSC Opera
5 Reviews
Departs Mar 02, 2026 from Durban, South Africa
Up to 1 deal including an Avoya Exclusive
Roundtrip
7-Night Africa Cruise
$693
MSC Cruises – MSC Musica
4 Reviews
Departs Mar 06, 2026 from Las Palmas, Spain
Up to 2 deals including an Avoya Exclusive
Roundtrip
7-Night Africa Cruise
$698
MSC Cruises – MSC Musica
4 Reviews
Departs Mar 07, 2026 from Funchal, Madeira Islands, Portugal
Up to 2 deals including an Avoya Exclusive
Roundtrip
7-Night Africa Cruise
$694
MSC Cruises – MSC Musica
4 Reviews
Departs Mar 08, 2026 from Santa Cruz de Tenerife, Spain
Up to 2 deals including an Avoya Exclusive
Roundtrip
4-Night Africa Cruise
$389
MSC Cruises – MSC Opera
5 Reviews
Departs Mar 09, 2026 from Durban, South Africa
Up to 1 deal including an Avoya Exclusive
Roundtrip
3-Night Africa Cruise
$309
MSC Cruises – MSC Opera
5 Reviews
Departs Mar 13, 2026 from Durban, South Africa
Up to 1 deal including an Avoya Exclusive
Roundtrip
7-Night Africa Cruise
$693
MSC Cruises – MSC Musica
4 Reviews
Departs Mar 13, 2026 from Las Palmas, Spain
Up to 2 deals including an Avoya Exclusive
Roundtrip
7-Night Africa Cruise
$698
MSC Cruises – MSC Musica
4 Reviews
Departs Mar 14, 2026 from Funchal, Madeira Islands, Portugal
Up to 2 deals including an Avoya Exclusive
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